Epigenetic & Fragmentomic Integration (GENyO)
Researchers at GENyO (Centre for Genomics and Oncological Research) in Granada have advanced "Next-Gen" liquid biopsy by combining DNA sequencing with fragmentomics.
Beyond Mutations: Spanish researchers are no longer just looking for "broken" genes. They are analyzing the fragmentation patterns of cell-free DNA (cfDNA), which act as a "metabolic fingerprint" of the tissue of origin.
Sensitive Detection: By integrating epigenomic approaches (methylation) with these fragment patterns, Spanish labs can now distinguish between malignant and benign conditions with a precision previously impossible with mutation-only tests.
The NovaSeq Initiative: Andalusia is currently running the first region-wide clinical trial using NovaSeq technology across all provinces to standardize these advanced protocols in public health.